Acts 17:6 (KJV) And when they found them not, they drew Jason and certain brethren unto the rulers of the city, crying, These that have turned the world upside down are come hither also;
The preaching of the gospel of the Lord Jesus Christ will turn the world upside down. When a person hears and receives the gospel, he becomes a new creature. Old things are passed away. He or she has new desires and old desires are put away. He or she begins to act different, talk different, dress different. His or her world is not the same. God is exalted. That certainly is upside down from the present world.